Linked Life Data

3791075

Source:http://linkedlifedata.com/resource/pubmed/id/3791075

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-2-3
pubmed:abstractText
Two hundred and seven boars entering a Record of Performance Test Station at New Hamburg, Ontario were screened for susceptibility to malignant hyperthermia or the porcine stress syndrome. Screening tests included the determination of whole blood creatine kinase levels by a commercially available test using the method of bioluminescence and a halothane challenge. The validity of the bioluminescent or whole blood creatine kinase test as a screening mechanism for malignant hyperthermia was evaluated in boars in a field trial. The susceptibility of these animals to malignant hyperthermia or the porcine stress syndrome was unknown at the time of the study. It was determined in the initial field trial that 76.3% or 158 of the 207 boars tested by the bioluminescent creatine kinase screening test were stress susceptible. In contrast, only one boar (0.5%) reacted to a standard five minute halothane challenge. After further examination of the commercial screening test, little correlation was found to exist between the bioluminescent and Rosalki methods of creatine kinase determination. The coefficient of analytical variation for the bioluminescent method of creatine kinase determination ranged from 17.6% at a mean of 359 LU to 21.9% at a mean of 318 LU. Similarly, the coefficient for the Rosalki technique ranged from 7.1% at a mean of 324 U/L to 14.0% at a mean of 64 U/L. In addition, little correlation was found to exist between creatine kinase levels as determined by the bioluminescent method and outcome to the halothane or halothane/succinylcholine challenge, age of boars in weeks or percentage gain in weight.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-1110219, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-1110862, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-1238567, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-23374, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-262774, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-391722, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-4381359, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-484409, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-5762120, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-6635547, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-6640412, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-6999950, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-738969, http://linkedlifedata.com/resource/pubmed/commentcorrection/3791075-990979
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0830-9000
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
494-501
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Evaluation of a commercial creatine kinase screening test for malignant hyperthermia (porcine stress syndrome).
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't