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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1987-1-6
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pubmed:abstractText |
Thirty two consecutive children who underwent surgery for suspected acute appendicitis, were treated with prophylactic metronidazole suppositories. A serum sample was taken at surgery to determine the serum concentration of the drug. After a preoperative dose of 15-20 mg/kg the minimal bactericidal concentration was achieved in almost all cases at the time of anesthetic induction. This drug showed an optimal biodisponibility when used rectally and no side-effects was noted. Neither a wound-infection, nor a wound-sepsis was reported and a satisfactory outcome was registered. We conclude that rectal dosing with metronidazole is effective for prophylactic wound infection in acute appendicitis.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0302-4342
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3789549-Administration, Rectal,
pubmed-meshheading:3789549-Adolescent,
pubmed-meshheading:3789549-Appendicitis,
pubmed-meshheading:3789549-Bacterial Infections,
pubmed-meshheading:3789549-Child,
pubmed-meshheading:3789549-Child, Preschool,
pubmed-meshheading:3789549-Drug Evaluation,
pubmed-meshheading:3789549-Female,
pubmed-meshheading:3789549-Humans,
pubmed-meshheading:3789549-Male,
pubmed-meshheading:3789549-Metronidazole,
pubmed-meshheading:3789549-Premedication,
pubmed-meshheading:3789549-Suppositories,
pubmed-meshheading:3789549-Surgical Wound Infection
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pubmed:year |
1986
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pubmed:articleTitle |
[Effectiveness of rectal metromidazole in acute infantile appendicitis].
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pubmed:publicationType |
Journal Article,
English Abstract
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