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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1987-1-15
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pubmed:abstractText |
Chlorine gas, spreading from a train derailment, caused the deaths of 8 persons and the hospitalization of 23 with sublethal respiratory injuries. Twenty-five others had at least one sign of lower respiratory abnormality but were not hospitalized. One hundred thirteen who were examined for gas effects in the forty-eight hours after exposure, including 20 of 23 of those hospitalized and 21 of 25 of those not hospitalized but with respiratory abnormality, participated in follow-up studies. Probability of admission to hospital was related to distance from the spill, but by 3 wk after exposure there was no detectable difference in lung function relating to distance or apparent severity of injury. In 60 adults tested multiple times over the following 6 yr, longitudinal change in lung function showed expected differences related to smoking but none related to distance or severity of injury. The average annual change in FEV was -34 ml/yr in current smokers and -18 ml/yr in ex and never-smokers. The lack of a discernible chlorine effect in this cohort accords with the findings in most previous studies. Without pre-exposure measurements, a single, lasting reduction in lung function cannot be excluded, but there is no evidence for a persisting abnormal rate of decline.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
134
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1190-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3789518-Accidents,
pubmed-meshheading:3789518-Acute Disease,
pubmed-meshheading:3789518-Adolescent,
pubmed-meshheading:3789518-Adult,
pubmed-meshheading:3789518-Aged,
pubmed-meshheading:3789518-Aged, 80 and over,
pubmed-meshheading:3789518-Child,
pubmed-meshheading:3789518-Chlorine,
pubmed-meshheading:3789518-Environmental Exposure,
pubmed-meshheading:3789518-Female,
pubmed-meshheading:3789518-Florida,
pubmed-meshheading:3789518-Humans,
pubmed-meshheading:3789518-Longitudinal Studies,
pubmed-meshheading:3789518-Lung,
pubmed-meshheading:3789518-Male,
pubmed-meshheading:3789518-Middle Aged,
pubmed-meshheading:3789518-Railroads,
pubmed-meshheading:3789518-Respiratory Tract Diseases,
pubmed-meshheading:3789518-Smoking,
pubmed-meshheading:3789518-Spirometry,
pubmed-meshheading:3789518-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
Lung function after acute chlorine exposure.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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