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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1986-12-31
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pubmed:abstractText |
The effect of dipyridamole on proteinuria was studied in 60 children with various renal diseases. A significant decrease in 24-hour urine protein excretion was observed within a few months after treatment in 32 (53%) of the patients with minimal or moderate mesangial proliferation. The effect was reproducible and parallelled by a reduction in plasma levels of beta-thromboglobulin. Renal function in patients significantly improved with the therapeutical effect. The appropriate dosage was 4-10 mg/kg daily and no serious toxicity was seen despite large dosage and even in long-term application. The data suggest that dipyridamole treatment appears safe and has a beneficial effect on proteinuria dependent on its effect on platelets in renal disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0028-2766
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
174-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3785481-Adolescent,
pubmed-meshheading:3785481-Child,
pubmed-meshheading:3785481-Child, Preschool,
pubmed-meshheading:3785481-Chronic Disease,
pubmed-meshheading:3785481-Dipyridamole,
pubmed-meshheading:3785481-Female,
pubmed-meshheading:3785481-Glomerulonephritis,
pubmed-meshheading:3785481-Glomerulonephritis, IGA,
pubmed-meshheading:3785481-Humans,
pubmed-meshheading:3785481-Male,
pubmed-meshheading:3785481-Proteinuria,
pubmed-meshheading:3785481-Purpura, Schoenlein-Henoch
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pubmed:year |
1986
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pubmed:articleTitle |
Effect of dipyridamole treatment on proteinuria in pediatric renal disease.
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pubmed:publicationType |
Journal Article,
Comparative Study
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