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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1986-12-29
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pubmed:abstractText |
Seven dog lower left lung lobes were statically inflated and perfused at a constant rate for each lobe with a perfusate in which the hematocrit was altered over a wide range. The permeability-surface area of urea was calculated from multiple indicator dilution curves using two separate injectates for each hematocrit level. One injectate contained only 125I-albumin as the vascular reference tracer and the other contained both 51Cr-erythrocytes and 125I-albumin as the vascular reference tracers; both contained [14C]urea as the permeating tracer. The results strongly indicate that the phenomenon of "erythrocyte trapping" of urea does not affect the calculation of urea permeability-surface area product provided the appropriate albumin-erythrocyte composite reference tracer is utilized in its calculation.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
8750-7587
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1383-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3781954-Animals,
pubmed-meshheading:3781954-Carbon Radioisotopes,
pubmed-meshheading:3781954-Cell Membrane Permeability,
pubmed-meshheading:3781954-Chromium Radioisotopes,
pubmed-meshheading:3781954-Dogs,
pubmed-meshheading:3781954-Erythrocytes,
pubmed-meshheading:3781954-Hematocrit,
pubmed-meshheading:3781954-Iodine Radioisotopes,
pubmed-meshheading:3781954-Lung,
pubmed-meshheading:3781954-Perfusion,
pubmed-meshheading:3781954-Surface Properties,
pubmed-meshheading:3781954-Urea
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pubmed:year |
1986
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pubmed:articleTitle |
Effect of perfusate hematocrit on urea permeability-surface area in isolated dog lung.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|