|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1987-1-22
|
|
pubmed:abstractText |
The effects of acetylcholine (ACh) on the release of [3H]5-hydroxytryptamine ([3H]5-HT) were investigated in synaptosomes prepared from rat cerebral cortex, hypothalamus and hippocampus and depolarized with 15 mM KCl under superfusion conditions. ACh inhibited the release of [3H]5-HT in all three brain areas. This effect was not modified by hexamethonium but was antagonized by atropine and by the non-classical antagonists pirenzepine and dicyclomine.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0014-2999
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
7
|
|
pubmed:volume |
129
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
353-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:3780848-Acetylcholine,
pubmed-meshheading:3780848-Animals,
pubmed-meshheading:3780848-Brain,
pubmed-meshheading:3780848-Cyclohexanecarboxylic Acids,
pubmed-meshheading:3780848-Dicyclomine,
pubmed-meshheading:3780848-Pirenzepine,
pubmed-meshheading:3780848-Rats,
pubmed-meshheading:3780848-Rats, Inbred Strains,
pubmed-meshheading:3780848-Receptors, Muscarinic,
pubmed-meshheading:3780848-Serotonin,
pubmed-meshheading:3780848-Synaptosomes
|
|
pubmed:year |
1986
|
|
pubmed:articleTitle |
Dicyclomine- and pirenzepine-sensitive muscarinic receptors mediate inhibition of [3H]serotonin release in different rat brain areas.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
