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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1987-1-15
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pubmed:abstractText |
Detailed clinical histories and cytogenetic investigations using short-term cultures are reported in three typical benign lipomas. Although a diploid (normal) karyotype was observed in two cases, a reciprocal chromosome translocation t(3;12)(q28;q14) was found in the third case, which was briefly reported previously. These data are discussed in light of a lipoma with similar karyotypic changes reported by Heim et al. and a similar translocation observed by us in malignant myxoid liposarcomas. The nonrandom involvement of segment 12q13-q14 in benign and malignant lipomatous tumors suggest a common basis for at least one of the possible multiple steps in the genesis of neoplastic processes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0165-4608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3779624-Adult,
pubmed-meshheading:3779624-Chromosomes, Human, Pair 12,
pubmed-meshheading:3779624-Chromosomes, Human, Pair 3,
pubmed-meshheading:3779624-Female,
pubmed-meshheading:3779624-Humans,
pubmed-meshheading:3779624-Karyotyping,
pubmed-meshheading:3779624-Lipoma,
pubmed-meshheading:3779624-Male,
pubmed-meshheading:3779624-Middle Aged,
pubmed-meshheading:3779624-Translocation, Genetic
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pubmed:year |
1986
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pubmed:articleTitle |
Cytogenetic studies of adipose tissue tumors. I. A benign lipoma with reciprocal translocation t(3;12)(q28;q14).
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pubmed:publicationType |
Journal Article,
Case Reports
|