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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-12-15
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pubmed:abstractText |
Proto-oncogene c-mos, the cellular homologue of the transforming gene of Moloney murine sarcoma virus, has been characterized by the lack of expression in a variety of differentiated tissues, possibly because of the existence of an inhibitory upstream sequence. We detected mos-related transcripts in undifferentiated embryonal carcinoma cells of pluripotential cell line 311. The sizes of three major transcripts detected were estimated to be 1.8, 4.6 and 6.1-kilobases (kb) by northern analysis. Furthermore, these transcriptions were suppressed when the cell differentiation was induced by retinoic acid. Taken together, the results suggest that mos product plays a role in early stages of development.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
477-84
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3778463-Animals,
pubmed-meshheading:3778463-Base Sequence,
pubmed-meshheading:3778463-Cell Differentiation,
pubmed-meshheading:3778463-Cell Line,
pubmed-meshheading:3778463-Cloning, Molecular,
pubmed-meshheading:3778463-Gene Expression Regulation,
pubmed-meshheading:3778463-Mice,
pubmed-meshheading:3778463-Nucleic Acid Hybridization,
pubmed-meshheading:3778463-Proto-Oncogenes,
pubmed-meshheading:3778463-Teratoma,
pubmed-meshheading:3778463-Transcription, Genetic
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pubmed:year |
1986
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pubmed:articleTitle |
Expression of c-mos proto-oncogene in undifferentiated teratocarcinoma cells.
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pubmed:publicationType |
Journal Article
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