Linked Life Data

3773331

Source:http://linkedlifedata.com/resource/pubmed/id/3773331

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-12-10
pubmed:abstractText
The effects of chronic administration of naloxone (120-150 micrograms X kg-1 X h-1) on the wheel running activity (WR) and on food and water intakes were studied in male Wistar rats subjected to a 2-h restricted feeding (1200-1400 h) schedule at 24 +/- 1 degrees C and LD 12:12 (L: 0600-1800 h) cycle. The restricted feeding significantly increased WR before and after the feeding time. Food and water intakes per day were reduced and body weight gradually decreased for the 2-week food restriction period. Food and water intakes appeared to be suppressed by naloxone, particularly shortly after the administration. The chronically administered naloxone slightly increased the 24-h WR. In the naloxone-treated rats, the fraction of WR before the feeding time (anticipatory activity) was significantly increased compared with saline-treated rats. The fraction of WR after the feeding time (succeeding activity) did not change. These results suggest that the endogenous opioid system may play a role in suppressing the excess increase in the anticipatory locomotor activity in the food restricted rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-521X
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
555-64
pubmed:dateRevised
2007-3-21
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Effects of chronic administration of naloxone on wheel running activity in rats under 2-h feeding schedule.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't