Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-11-24
pubmed:abstractText
The effect of actinomycin D (0.4 mg/kg) on radiation-induced lung damage in the mouse was investigated. The drug was administered either 4 weeks before, immediately after, or 16 weeks after single doses of 240 kV X-rays applied to the thorax of CBA mice. Lung damage was assessed by measuring respiration rate, with a whole body plethysmograph. Dose-response curves were obtained at 2-week intervals from 12 to 40 weeks after irradiation. Actinomycin D had no significant effect on respiration rate in this study. A summary of other experimental studies is included which shows conflicting results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0277-5379
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
577-82
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Actinomycin D and radiation: effects on mouse lung.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't