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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1986-10-31
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pubmed:abstractText |
Heparin enhances strongly the mitogenic properties of human acidic fibroblast growth factor (h-aFGF) on hamster fibroblast (CCL 39) or bovine lens epithelial cells (BEL). We report here that a synthetic heparin pentasaccharide with high affinity for antithrombin III has the same effect as heparin at about the same concentration. Thus a pentasaccharidic sequence may represent the shortest heparin structure which interacts with h-aFGF.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-291X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
728-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3767984-Animals,
pubmed-meshheading:3767984-Antithrombin III,
pubmed-meshheading:3767984-Carbohydrate Sequence,
pubmed-meshheading:3767984-Cattle,
pubmed-meshheading:3767984-Cell Line,
pubmed-meshheading:3767984-Cricetinae,
pubmed-meshheading:3767984-Epithelium,
pubmed-meshheading:3767984-Fibroblast Growth Factors,
pubmed-meshheading:3767984-Fibroblasts,
pubmed-meshheading:3767984-Heparin,
pubmed-meshheading:3767984-Humans,
pubmed-meshheading:3767984-Lens, Crystalline,
pubmed-meshheading:3767984-Structure-Activity Relationship
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pubmed:year |
1986
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pubmed:articleTitle |
Structure activity relationship in heparin: stimulation of non-vascular cells by a synthetic heparin pentasaccharide in cooperation with human acidic fibroblast growth factors.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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