Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1986-11-12
pubmed:abstractText
Imidocarb dipropionate (IDP), a potent prophylactic drug against Babesia bovis infections in cattle, was tested for its effect on the infectivity and immunogenicity of a live B. bovis vaccine marketed in Australia. At the recommended prophylactic dose rate of 3 mg/kg, IDP suppressed infectivity of the vaccine for at least 6 weeks. The vaccine infected all cattle inoculated either 8 weeks after treatment with 3 mg/kg, or 4 weeks after treatment with the recommended therapeutic dose of 1.2 mg/kg. These infections were, however, partially suppressed and the level of immunity to a subsequent heterologous virulent challenge was reduced. Cattle that failed to become infected after vaccination were fully susceptible to the challenge. It is concluded that where B. bovis vaccination is contemplated, prophylactic use of IDP should be avoided.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0005-0423
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
174-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Effect of imidocarb dipropionate prophylaxis on the infectivity and immunogenicity of a Babesia bovis vaccine in cattle.
pubmed:publicationType
Journal Article