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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1986-11-13
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pubmed:abstractText |
In alpha-thalassemia, deletion or inactivation of one, two, three, or all four alpha-genes causes, respectively, silent carrier state (-alpha/alpha alpha); alpha-thalassemia trait (--/alpha alpha in Orientals, and -alpha/-alpha in blacks); Hb H disease (--/-alpha); and Hb Bart's hydrops fetalis (--/--). We have described a case of Hb H disease with Hb Constant Spring (--/alpha alpha cs) in a Laotian child whose father had alpha-thalassemia trait and whose mother was a carrier of Hb CS, a mutant hemoglobin produced in minimal amounts. Since alpha-thalassemia is highly prevalent in Southeast Asia, physicians should become alert to the potential occurrence of Hb H disease and Hb Bart's hydrops fetalis in the new Oriental immigrants and their progeny.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0038-4348
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
79
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1289-92
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3764529-Hemoglobins, Abnormal,
pubmed-meshheading:3764529-Heterozygote Detection,
pubmed-meshheading:3764529-Humans,
pubmed-meshheading:3764529-Infant,
pubmed-meshheading:3764529-Laos,
pubmed-meshheading:3764529-Refugees,
pubmed-meshheading:3764529-Thalassemia,
pubmed-meshheading:3764529-United States
|
pubmed:year |
1986
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pubmed:articleTitle |
Hemoglobin H disease with hemoglobin Constant Spring in a child of Laotian extraction.
|
pubmed:publicationType |
Journal Article,
Case Reports
|