Linked Life Data

3763129

Source:http://linkedlifedata.com/resource/pubmed/id/3763129

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1986-11-12
pubmed:abstractText
Respiratory arrest is a serious complication of retrobulbar anesthesia. We have prospectively followed 3123 retrobulbar injections to determine the incidence of respiratory arrest and identify possible risk factors. Injections contained either 2% or 4% lidocaine with 0.75% bupivacaine (Marcaine) in a 50:50 mixture by volume (total 10 cc.) to which a 1 ml ampule of hyaluronidase (150 NF units) was added. Use of 4% lidocaine gave a significantly higher incidence of respiratory arrest than 2% lidocaine (0.79% vs. 0.09%; P = 0.003, Fisher's exact test). Serum levels of lidocaine and bupivacaine of patients who arrested were not elevated significantly compared to 20 control patients. All levels were well below accepted levels of toxicity. Thus, 4% lidocaine increases the risk of respiratory arrest. These results suggest the mechanism is not direct intravascular or central nervous system injection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0161-6420
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
867-70
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Respiratory arrest following retrobulbar anesthesia.
pubmed:publicationType
Journal Article