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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3 Pt 1
|
pubmed:dateCreated |
1986-11-4
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pubmed:abstractText |
Eight adult subjects with asthma had isocapnic cold air challenges on 4 different days. Three consecutive tests were performed on each visit with functional recovery between tests. Subjects were asked to breathe dry cold air (-20 degrees C) for progressively increasing levels of minute ventilation (7.5, 15, 30, and 60 L/min and maximal voluntary ventilation) until a 20% fall in FEV1 had been reached or when maximal voluntary ventilation was done. FEV1 was assessed between each level. The doses of respiratory heat exchange and minute ventilation causing 10%, 15%, and 20% changes in FEV1 were interpolated from dose-response curves. The within- and between-day 95% confidence intervals based on a single determination on the loge scale varied from +/- 0.32 to 0.59 for the indices derived from respiratory heat exchange. Reproducibility of the between-day results was more satisfactory than for the corresponding within-day assessments. No significant within-day tachyphylaxis was demonstrated for these indices.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0091-6749
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
78
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
379-87
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:3760397-Adolescent,
pubmed-meshheading:3760397-Adult,
pubmed-meshheading:3760397-Asthma,
pubmed-meshheading:3760397-Body Temperature Regulation,
pubmed-meshheading:3760397-Bronchi,
pubmed-meshheading:3760397-Cold Temperature,
pubmed-meshheading:3760397-Female,
pubmed-meshheading:3760397-Forced Expiratory Volume,
pubmed-meshheading:3760397-Humans,
pubmed-meshheading:3760397-Male,
pubmed-meshheading:3760397-Middle Aged,
pubmed-meshheading:3760397-Tachyphylaxis,
pubmed-meshheading:3760397-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
Within- and between-day reproducibility of isocapnic cold air challenges in subjects with asthma.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|