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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1986-11-18
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pubmed:abstractText |
In a study of sleep-disordered breathing among 139 elderly individuals, sleep apnea (defined as 5 or more apneas per hour) occurred in 34 (41.7%) Alzheimer's subjects compared with 56 (5.4%) healthy controls, 35 (11.4%) depressive subjects, and 24 (16.7%) patients with mixed symptoms of both cognitive impairment and depression (p less than .001). Alzheimer's patients had a significantly higher proportion of NREM-related than REM-related apnea. Moreover, a significant (p less than .01) positive correlation between the apnea index and severity of dementia, as measured by the Blessed Dementia Rating Scale, was found in apnea-positive Alzheimer's patients, as well as in the entire sample of Alzheimer's patients (p less than .05). No such correlation was found in the mixed-symptoms group. Possible clinical and neuropathologic implications are discussed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0160-6689
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
499-503
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3759914-Aged,
pubmed-meshheading:3759914-Aged, 80 and over,
pubmed-meshheading:3759914-Aging,
pubmed-meshheading:3759914-Alzheimer Disease,
pubmed-meshheading:3759914-Cognition Disorders,
pubmed-meshheading:3759914-Depressive Disorder,
pubmed-meshheading:3759914-Electroencephalography,
pubmed-meshheading:3759914-Female,
pubmed-meshheading:3759914-Humans,
pubmed-meshheading:3759914-Male,
pubmed-meshheading:3759914-Middle Aged,
pubmed-meshheading:3759914-Sleep,
pubmed-meshheading:3759914-Sleep Apnea Syndromes
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pubmed:year |
1986
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pubmed:articleTitle |
Sleep-disordered breathing in normal and pathologic aging.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|