Linked Life Data

3755611

Source:http://linkedlifedata.com/resource/pubmed/id/3755611

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-10-6
pubmed:abstractText
Biopsies from 63 patients, 40 with mycosis fungoides (MF) and 23 with other lymphocytic infiltrates, were stained with a panel of monoclonal antibodies to differentiation antigens (OKT10, Leu 8), to activation antigens (OKT9), and to an antigen expressed by all dividing cells (Ki67) to establish whether this panel was of value in the diagnosis of mycosis fungoides. None of these antibodies used in isolation was found to give a staining pattern specific for mycosis fungoides, but the phenotype Leu 3a+, OKT9+, Leu 8- of the majority of lymphocytes in the cutaneous infiltrate was strongly suggestive. The presence of Leu 3a+ Leu 8- lymphocytes is of particular interest in that in the peripheral blood both of normal subjects and of MF patients Leu 3a+ lymphocytes also are predominantly Leu 8+, were the lymphocytes in the cutaneous infiltrates of the non-MF infiltrates included in this study.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0007-0963
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
151-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
An assessment of the diagnostic value of the monoclonal antibodies Leu 8, OKT9, OKT10 and Ki67 in cutaneous lymphocytic infiltrates.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't