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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1986-7-2
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pubmed:abstractText |
Analysis of myosin light chain kinase (MLCK) activity in tibialis anterior muscles of the rabbit revealed that chronic stimulation at a frequency of 10 Hz for 24 h per day reduced the enzyme activity in a time-dependent manner. Since fast twitch muscle contains significantly more myosin light chain kinase than slow twitch muscle, the observed reductions are consistent with the type of fast-to-slow transformation observed for other type-specific muscle characteristics. The present data also indicate that the stimulation-induced decrease in MLCK activity precedes the fast-to-slow conversion of the myosin molecule as judged by pyrophosphate-polyacrylamide gel electrophoresis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0014-5793
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
12
|
pubmed:volume |
200
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
352-4
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:3754822-Animals,
pubmed-meshheading:3754822-Electric Stimulation,
pubmed-meshheading:3754822-Muscle Contraction,
pubmed-meshheading:3754822-Muscles,
pubmed-meshheading:3754822-Myosin-Light-Chain Kinase,
pubmed-meshheading:3754822-Myosins,
pubmed-meshheading:3754822-Phosphorylation,
pubmed-meshheading:3754822-Protein Kinases,
pubmed-meshheading:3754822-Rabbits
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pubmed:year |
1986
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pubmed:articleTitle |
Decrease in myosin light chain kinase activity of rabbit fast muscle by chronic stimulation.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|