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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-10-9
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pubmed:abstractText |
Pulmonary function tests were performed on a total of 125 healthy infants younger than 25 postconception (pc) months of age. Maximal expiratory flow at functional residual capacity (VmaxFRC) was measured from partial expiratory flow-volume curves, and functional residual capacity (FRC) was measured by the helium dilution technique. There was a highly significant (p less than 0.01) linear regression for both VmaxFRC and FRC with increasing body length. The highest size-corrected flows (VmaxFRC/FRC) were obtained in the healthy premature (2.7 FRC/s, n = 6) and full-term (2.5 FRC/s, n = 5) infants, and there was a relatively constant value between 13 and 25 pc months of age (1.2 FRC/s), which was similar to those reported in older children and adults. In an age-matched group of infants 10 to 16 pc months of age, females had both higher absolute flows (126 versus 102 ml/s, p less than 0.03) and size-corrected flows (1.4 versus 1.0 FRC/s, p less than 0.001) than did males. These physiologic data support the concepts that neonates have proportionately larger airways relative to their lung volume at FRC, infants have size-corrected flows similar to those in older children and adults, and female infants have proportionately larger airways relative to their lung size than do male infants.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
513-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3752707-Chloral Hydrate,
pubmed-meshheading:3752707-Female,
pubmed-meshheading:3752707-Functional Residual Capacity,
pubmed-meshheading:3752707-Humans,
pubmed-meshheading:3752707-Infant,
pubmed-meshheading:3752707-Infant, Newborn,
pubmed-meshheading:3752707-Lung,
pubmed-meshheading:3752707-Male,
pubmed-meshheading:3752707-Peak Expiratory Flow Rate,
pubmed-meshheading:3752707-Pulmonary Ventilation,
pubmed-meshheading:3752707-Respiration,
pubmed-meshheading:3752707-Tidal Volume
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pubmed:year |
1986
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pubmed:articleTitle |
Physiologic growth and development of the lung during the first year of life.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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