Linked Life Data

3752278

Source:http://linkedlifedata.com/resource/pubmed/id/3752278

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Pt 2
pubmed:dateCreated
1986-10-21
pubmed:abstractText
The impact of the adrenal system on urinary rhythms was investigated in adrenalectomized (ADX) rats under various experimental conditions. During a 12:12 light-dark cycle the acrophases were shifted in ADX rats with respect to control rats. Under constant light conditions ADX rats displayed free-running rhythms, similar to those of control rats. The periods were stable in blind rats but not in rats maintained on a constant light cycle. The abrupt change in period, which occurred after approximately 8 days, suggests a stage of internal desynchronization. A 6-h delay in the administration of corticosterone to ADX rats caused a delay shift of the acrophases. A single intraperitoneal injection of corticosterone in blind free-running ADX rats caused delay or advance shifts so that we could construct phase-response curves for the various excretory rhythms. These observations indicate that the adrenals are not essential for the establishment of the urinary rhythms; however, corticosterone influences the phase setting of these rhythms. The site of action is probably the X pacemaker (controlling the body temperature rhythm), although we cannot totally exclude an additional effect on secondary (renal) oscillators.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
251
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R441-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Circadian urinary excretion rhythms in adrenalectomized rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't