Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1986-10-20
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pubmed:abstractText |
The etiology of insulin-dependent diabetes mellitus remains obscure. In an attempt to clarify some aspects of the epidemiology, including its compatibility with an acute infectious process, the authors undertook in-depth analyses of childhood cases accumulated in a population-based register in Montreal during the period from 1971-1983. Incidence rates increased with age until puberty, at which point they plateaued and decreased. There was no overall difference in incidence between males and females; however, the rate for females peaked approximately two years before the rate for males. While there was some variation over time, there was no evidence of a long-term trend, nor was the yearly variation impressive in magnitude. The findings further indicate that the disease is not characterized by explosive outbreaks. There was slight seasonality, with a 28% higher rate of onset in fall and winter than in spring and summer. There was some evidence of space-time clustering in 1971-1973, but not thereafter. Taken as a whole, these findings do not support the hypothesis that a significant portion of insulin-dependent diabetes is caused by an acute infectious process.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0002-9262
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
124
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
545-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3752050-Adolescent,
pubmed-meshheading:3752050-Age Factors,
pubmed-meshheading:3752050-Child,
pubmed-meshheading:3752050-Child, Preschool,
pubmed-meshheading:3752050-Diabetes Mellitus, Type 1,
pubmed-meshheading:3752050-Female,
pubmed-meshheading:3752050-Humans,
pubmed-meshheading:3752050-Infant,
pubmed-meshheading:3752050-Infant, Newborn,
pubmed-meshheading:3752050-Male,
pubmed-meshheading:3752050-Quebec,
pubmed-meshheading:3752050-Retrospective Studies,
pubmed-meshheading:3752050-Seasons,
pubmed-meshheading:3752050-Sex Factors,
pubmed-meshheading:3752050-Space-Time Clustering
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pubmed:year |
1986
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pubmed:articleTitle |
The distribution of type I (insulin-dependent) diabetes mellitus by age, sex, secular trend, seasonality, time clusters, and space-time clusters: evidence from Montreal, 1971-1983.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|