Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1986-10-15
|
pubmed:abstractText |
Intracameral slowly mixed bolus doses of 10 micrograms of 1-epinephrine or 1-norepinephrine bitartrate significantly increased total outflow facility by similar percentages in ciliary muscle disinserted and non-disinserted living cynomolgus monkey eyes (approximately 20% for epinephrine, 30% for norepinephrine); smaller or larger bolus doses (0.1, 1, 50 micrograms) either had no effect or tended to decrease facility. Bolus doses of dl-isoproterenol sulphate (0.1, 0.2, 10, 50 micrograms) or 1-isoproterenol hydrochloride (0.1, 1, 10 micrograms) had no effect in either type of eye. Rapidly mixed relatively maintained intracameral concentrations of dl(0.1, 1 micrograms/ml)- or l(0.1, 1, 10 micrograms/ml)-isoproterenol had no effect in surgically untouched eyes. All catecholamine solutions were stable under the experimental conditions.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0001-639X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
64
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
356-63
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:3751525-Animals,
pubmed-meshheading:3751525-Anterior Chamber,
pubmed-meshheading:3751525-Aqueous Humor,
pubmed-meshheading:3751525-Dose-Response Relationship, Drug,
pubmed-meshheading:3751525-Epinephrine,
pubmed-meshheading:3751525-Female,
pubmed-meshheading:3751525-Iris,
pubmed-meshheading:3751525-Isoproterenol,
pubmed-meshheading:3751525-Macaca fascicularis,
pubmed-meshheading:3751525-Male,
pubmed-meshheading:3751525-Norepinephrine,
pubmed-meshheading:3751525-Oculomotor Muscles
|
pubmed:year |
1986
|
pubmed:articleTitle |
Epinephrine, norepinephrine, and isoproterenol dose-outflow facility response relationships in cynomolgus monkey eyes with and without ciliary muscle retrodisplacement.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|