Linked Life Data

3748346

Source:http://linkedlifedata.com/resource/pubmed/id/3748346

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-10-20
pubmed:abstractText
There is a need to monitor the functional status of the motor pathways well enough to predict the state of that function during operations and in injured or diseased patients. We previously reported that a motor evoked potential (MEP) can be produced by direct or transcranial stimulation of the motor cortex in both cats and humans. This signal descends through both the dorsolateral and ventral spinal cord and is primarily localized in the pyramidal tracts, producing a peripheral nerve signal and an electromyogram (EMG) response. It is more sensitive to injury than the somatosensory evoked potential (SEP). We report here that one can stimulate the cerebellar cortex, either directly or transcranially, and produce a descending signal in the spinal cord that has different characteristics from the MEP. The cerebellar evoked potential (CEP), located in the dorsolateral and the ventral cord, has an earlier latency and a faster conduction velocity than the MEP. It is predominantly ipsilateral with some contralateral components and also produces EMG responses. In the peripheral nerves, the CEP often produces a pattern of several waves that is different from the one or two predominant contralateral waves of the MEP. The CEP is not diminished by pyramidotomy. It arises from two sites on the cerebellar cortex, medial and lateral. The pathways activated may be the vestibulospinal, rubrospinal, reticulospinal, and fastigiospinal systems. This test seems to offer a monitor of selected motor pathways in the spinal cord largely separate from and complementary to the MEP. The ventral pathways activated probably include those demonstrated to be most essential to basic ambulation after spinal cord injury in primates. Also of importance, one type of evoked potential can facilitate another, which provides additional diagnostic tests. The CEP should be of investigative and clinical value.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0148-396X
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-76
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Nonpyramidal motor activation produced by stimulation of the cerebellum, direct or transcranial: a cerebellar evoked potential.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't