rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1986-9-30
|
pubmed:abstractText |
Seventy-eight patients with endoscopically proven duodenal ulcer were randomly allocated to be treated with a medium dose of liquid aluminum-magnesium antacid (75 ml in five daily doses) or cimetidine (400 mg twice daily) for 4 weeks in a prospective double-blind, double-dummy study. Healing rates at completion of trial were 66.7% in the cimetidine-treated group and 71.8% in the antacid group (p, ns). Both treatments were equally effective in relieving ulcer symptoms. Among the patient variables considered, only cigarette smoking was found to have a significant negative effect on ulcer healing. These results indicate that medium doses of antacids are as effective as cimetidine in the short-term treatment of duodenal ulcer.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0192-0790
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
141-5
|
pubmed:dateRevised |
2009-11-2
|
pubmed:meshHeading |
pubmed-meshheading:3745847-Adult,
pubmed-meshheading:3745847-Aluminum Hydroxide,
pubmed-meshheading:3745847-Antacids,
pubmed-meshheading:3745847-Cimetidine,
pubmed-meshheading:3745847-Double-Blind Method,
pubmed-meshheading:3745847-Drug Combinations,
pubmed-meshheading:3745847-Duodenal Ulcer,
pubmed-meshheading:3745847-Female,
pubmed-meshheading:3745847-Humans,
pubmed-meshheading:3745847-Magnesium,
pubmed-meshheading:3745847-Magnesium Hydroxide,
pubmed-meshheading:3745847-Male,
pubmed-meshheading:3745847-Middle Aged,
pubmed-meshheading:3745847-Prospective Studies,
pubmed-meshheading:3745847-Random Allocation,
pubmed-meshheading:3745847-Smoking
|
pubmed:year |
1986
|
pubmed:articleTitle |
Medium-dose antacids versus cimetidine in the short-term treatment of duodenal ulcer.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|