Linked Life Data

3745707

Source:http://linkedlifedata.com/resource/pubmed/id/3745707

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-9-26
pubmed:abstractText
It has been speculated that neonatal coarctation results from postnatal constriction of the aortic isthmus and ductus arteriosus. However, aortic arch hypoplasia is present in some neonates with coarctation and is presumed to be due to decreased aortic arch blood flow in utero. To measure the degree of aortic arch hypoplasia and to analyze the distribution of blood flow in neonatal coarctation, quantitative morphometric analysis of the great vessels from two-dimensional echocardiograms was performed in 14 neonates with isolated coarctation and 14 normal control neonates, all less than 1 month old. Measurements of the aortic valve, pulmonary valve, ascending aorta, transverse aortic arch between the carotid and subclavian arteries, aortic isthmus, descending aorta, main pulmonary artery and brachiocephalic vessels were obtained to the nearest 0.5 mm. In coarctation patients the transverse arch and isthmus were significantly smaller than in control subjects (p less than 0.001). In addition, pulmonary valve and main pulmonary artery diameters were significantly greater in neonates with coarctation than in normal neonates. Transverse arch hypoplasia and increased pulmonary valve and pulmonary artery diameters are present in neonates with coarctation. This suggests decreased aortic arch flow and increased pulmonary and ductus arteriosus flow in utero, which produce a characteristic echocardiographic appearance of transverse arch hypoplasia with a large main pulmonary artery.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0735-1097
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
616-20
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Quantitative morphology of the aortic arch in neonatal coarctation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.