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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1986-10-2
|
pubmed:abstractText |
The role of radiation in the treatment of squamous cell carcinoma of the esophagus was examined in a review of 74 patients treated with curative intent between 1974 and 1981. Aspects studied included the pattern of failure, the use of radiation as a surgical adjuvant, achievement of palliation, and the presence of technical or clinical factors predicting for a better outcome. The group was divided into 9 patients irradiated after esophageal resection, 14 patients irradiated before resection, and 51 patients treated with radiation and no resection. Median and 2-year survival rates among 51 patients treated by radiation without esophagectomy were 8.8 months and 11%, whereas they were 9.7 months and 0% in patients treated by radiation followed by resection, and 9.5 months and 28% in patients undergoing resection followed by radiation. Local failures were suffered in 28/51 patients treated without esophagectomy with rates of 2/4, 7/10, 7/15, and 5/10 after 50-55 Gy, 55-60 Gy, 60-65 Gy, and 65-69 Gy, respectively. Although prognosis for patients presenting with unresectable disease remains poor, a somewhat better outcome may be expected in patients treated with postoperative radiation after potentially unfavorable resections. Other predictors include sex and disease stage.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0008-543X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1208-13
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3742445-Carcinoma, Squamous Cell,
pubmed-meshheading:3742445-Combined Modality Therapy,
pubmed-meshheading:3742445-Esophageal Neoplasms,
pubmed-meshheading:3742445-Female,
pubmed-meshheading:3742445-Humans,
pubmed-meshheading:3742445-Male,
pubmed-meshheading:3742445-Prognosis,
pubmed-meshheading:3742445-Radiotherapy
|
pubmed:year |
1986
|
pubmed:articleTitle |
Radiation therapy alone or in combination with surgery in the treatment of carcinoma of the esophagus.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|