Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1986-9-17
pubmed:abstractText
A solution containing synthetic liposomes was injected into rabbit knee joints. This induced light and electron microscopic findings very similar to those seen in acute or chronic arthritis, not attributable to any mechanism other than to spherulites, in humans. Synovial fluid studies revealed leukocytosis and abundant extracellular, and/or intracellular positively birefringent spherulites, which appeared as Maltese crosses. Histologic studies of synovial membranes showed infiltration with polymorphonuclear neutrophils or mononuclear cells. Examination of the synovial fluids and synovial membranes by electron microscopy revealed intracellular multilayered membranous arrays of varying shapes. These observations suggest that further consideration should be given to a phlogistic role for similar spherulites found in some patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0004-3591
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
889-96
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Liposome-induced synovitis in rabbits. Light and electron microscopic studies.
pubmed:publicationType
Journal Article