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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1986-9-17
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pubmed:abstractText |
Twenty out of 40 patients with onyalai admitted to Rundu State Hospital, Kavango, SWA/Namibia, were randomized to receive a vincristine sulphate bolus of 1.5 mg/m2 or an equivalent volume of normal saline intravenously on days 8 and 15 when haemorrhage or a platelet count of less than 50 X 10(9)/l persisted for more than 1 week after admission. All patients were observed in hospital for at least 21 days. Five out of 10 patients who received vincristine achieved a platelet count in excess of 100 X 10(9)/l on day 21 and only 2 out of 10 patients who received placebo achieved a similar rise in the platelet count. Two patients, neither of whom was treated with vincristine, died of cerebral haemorrhage.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0256-9574
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
70
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
201-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3738655-Adolescent,
pubmed-meshheading:3738655-Adult,
pubmed-meshheading:3738655-Child,
pubmed-meshheading:3738655-Child, Preschool,
pubmed-meshheading:3738655-Drug Evaluation,
pubmed-meshheading:3738655-Female,
pubmed-meshheading:3738655-Humans,
pubmed-meshheading:3738655-Injections, Intravenous,
pubmed-meshheading:3738655-Male,
pubmed-meshheading:3738655-Middle Aged,
pubmed-meshheading:3738655-Platelet Count,
pubmed-meshheading:3738655-Prospective Studies,
pubmed-meshheading:3738655-Purpura, Thrombocytopenic,
pubmed-meshheading:3738655-Random Allocation,
pubmed-meshheading:3738655-Time Factors,
pubmed-meshheading:3738655-Vincristine
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pubmed:year |
1986
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pubmed:articleTitle |
Onyalai--therapeutic effects of vincristine sulphate. A prospective randomized trial.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|