Linked Life Data

3730823

Source:http://linkedlifedata.com/resource/pubmed/id/3730823

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-9-16
pubmed:abstractText
The activity of 50 histologically identified neurones of the median preoptic area (MPO) was recorded simultaneously with blood pressure monitoring. The responsiveness of these neurones was investigated with increasing doses (25-100 ng/ml/kg) of intravenously applied angiotensin II (ANG II). Mean blood pressure rose in a dose-dependent manner (between 3.9 +/- 0.5 and 18.6 +/- 2.6 mm Hg) whereas the rise in firing frequency of MPO neurones (between 47 and 105% of spontaneous discharge) was not dose-related. The latency of neuronal response decreased according to the dose applied: at the lowest dose of angiotensin it was longer (105 +/- 20 s) than at the highest dose (26 +/- 8 s). These findings suggest that MPO neurones are sensitive to ANG II-haemodynamic changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
375
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
230-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Median preoptic neurones are sensitive to blood pressure changes induced by peripheral angiotensin II.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't