Linked Life Data

3726175

Source:http://linkedlifedata.com/resource/pubmed/id/3726175

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-8-6
pubmed:abstractText
The functions of polymorphonuclear leukocytes from tobacco smokers are altered compared to those from nonsmokers. Since neutrophil chemotaxis and oxidative metabolism are mediated by surface receptors, we studied the association of the chemotactic peptide formyl Met-Leu-Phe with neutrophils from smokers and non-smokers. An apparently single class of binding sites was observed in neutrophils from all the non-smokers, whereas upwardly curving Scatchard plots were obtained for binding to smokers' cells. Thus changes at the receptor level may be responsible for the previously observed alterations in smoker neutrophil function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0167-0115
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-51
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Altered chemotactic peptide binding in tobacco smokers' neutrophils.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't