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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-8-20
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pubmed:abstractText |
At four involved hospitals 16 children were treated with Metaiodobenzylguanidine (131J-MIBG). These children had a relapse of neuroblastoma stage III or IV or did not respond sufficiently to chemotherapy. In 10 children extreme bone pain disappeared and they became free of fever during the MIBG-treatment. 10 children responded to the therapy demonstrated either by decrease of the solid tumor part or by decrease of catecholamines in urine or plasma or by decrease of bone-marrow involvement. One patient reached a complete remission continuing up to present time (longer than 180 days). 9 patients died meanwhile of tumor progression. 131J-MIBG is an effective instrument, to get a decrease of the tumor up to a complete remission in extensively pretreated patients with tumor relapse, which are refractory to chemotherapy.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8630
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
198
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
230-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3723987-3-Iodobenzylguanidine,
pubmed-meshheading:3723987-Adolescent,
pubmed-meshheading:3723987-Bone Marrow,
pubmed-meshheading:3723987-Catecholamines,
pubmed-meshheading:3723987-Cell Survival,
pubmed-meshheading:3723987-Child,
pubmed-meshheading:3723987-Child, Preschool,
pubmed-meshheading:3723987-Combined Modality Therapy,
pubmed-meshheading:3723987-Female,
pubmed-meshheading:3723987-Follow-Up Studies,
pubmed-meshheading:3723987-Humans,
pubmed-meshheading:3723987-Iodine Radioisotopes,
pubmed-meshheading:3723987-Iodobenzenes,
pubmed-meshheading:3723987-Male,
pubmed-meshheading:3723987-Neoplasm Metastasis,
pubmed-meshheading:3723987-Neoplasm Staging,
pubmed-meshheading:3723987-Neuroblastoma
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pubmed:articleTitle |
[Initial experiences in the treatment of children with metastatic and recurrent neuroblastoma using meta-iodobenzylguanidine].
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pubmed:publicationType |
Journal Article,
English Abstract
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