Linked Life Data

3720839

Source:http://linkedlifedata.com/resource/pubmed/id/3720839

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1986-8-15
pubmed:abstractText
Morphine produced a dose-dependent increase in the activity of norepinephrine-containing locus coeruleus neurons recorded from mouse brain slices in vitro. The response was not changed in a low calcium-high magnesium incubation medium, indicating that the observed effects are the result of a direct action of morphine on locus coeruleus neurons. When the mice were anesthetized with chloral hydrate prior to preparation of tissue slices, morphine produced a dose-dependent suppression of noradrenergic neuronal activity. These studies suggest that previous data showing a decrease in activity of locus coeruleus neurons following incubation with morphine in vitro are due to the use of anesthesia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-92
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Morphine increases locus coeruleus noradrenergic neuronal activity in vitro.
pubmed:publicationType
Journal Article, In Vitro