| pubmed-article:3718018 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C0005974 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C0019134 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C0019588 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C0073994 | lld:lifeskim |
| pubmed-article:3718018 | lifeskim:mentions | umls-concept:C2825501 | lld:lifeskim |
| pubmed-article:3718018 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3718018 | pubmed:dateCreated | 1986-6-27 | lld:pubmed |
| pubmed-article:3718018 | pubmed:abstractText | A quantitative mouse calvarial bone resorption assay was employed to investigate the effects of the mast cell products, heparin and histamine, and of salmon calcitonin. 'Amorphous' heparin, containing a range of molecular weight fractions, inhibited resorption by 15-20% at concentrations of 0.75-5.0 mg/ml. A 'defined' heparin species of mol.wt 13 500 inhibited resorption by 14-28% at 10(-5)-10(-4) mol/l. Histamine inhibited resorption by 19-55% at 10(-3)-10(-2) mol/l. It is proposed that heparin and histamine depress coupled bone resorption and formation and may lead to net loss of bone. Salmon calcitonin inhibited resorption at concentrations as low as 10 pg/ml. 'Amorphous' (but not 'defined') heparin blunted calcitonin induced inhibition of bone resorption and may derepress osteoclasts. | lld:pubmed |
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| pubmed-article:3718018 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3718018 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3718018 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3718018 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3718018 | pubmed:month | May | lld:pubmed |
| pubmed-article:3718018 | pubmed:issn | 0003-4967 | lld:pubmed |
| pubmed-article:3718018 | pubmed:author | pubmed-author:WrightJ KJK | lld:pubmed |
| pubmed-article:3718018 | pubmed:author | pubmed-author:HazlemanB LBL | lld:pubmed |
| pubmed-article:3718018 | pubmed:author | pubmed-author:CrispA JAJ | lld:pubmed |
| pubmed-article:3718018 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3718018 | pubmed:volume | 45 | lld:pubmed |
| pubmed-article:3718018 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3718018 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3718018 | pubmed:pagination | 422-7 | lld:pubmed |
| pubmed-article:3718018 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:3718018 | pubmed:meshHeading | pubmed-meshheading:3718018-... | lld:pubmed |
| pubmed-article:3718018 | pubmed:meshHeading | pubmed-meshheading:3718018-... | lld:pubmed |
| pubmed-article:3718018 | pubmed:meshHeading | pubmed-meshheading:3718018-... | lld:pubmed |
| pubmed-article:3718018 | pubmed:meshHeading | pubmed-meshheading:3718018-... | lld:pubmed |
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| pubmed-article:3718018 | pubmed:meshHeading | pubmed-meshheading:3718018-... | lld:pubmed |
| pubmed-article:3718018 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3718018 | pubmed:articleTitle | Effects of heparin, histamine, and salmon calcitonin on mouse calvarial bone resorption. | lld:pubmed |
| pubmed-article:3718018 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3718018 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3718018 | lld:pubmed |
