Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1986-6-27
pubmed:abstractText
To test the hypothesis that patients with normal serum levels of creatine kinase (CK) but elevated percentages of MB isoenzyme fractions in suspected myocardial infarction may have sustained clinically significant events, we studied the hospital course of 347 consecutive patients admitted with suspected myocardial infarction. Two hundred twenty-three patients had normal CK levels (182 +/- 44 IU) and normal MB percentages (normal group), 68 had elevated levels of both CK (1395 +/- 178 IU) and MB percentage (10.5 +/- 0.6) (macroinfarction group), and 40 had normal CK levels (96 +/- 7 IU) but elevated MB percentages (9.6 +/- 0.5) with typical enzyme curves (microinfarction group). Compared to the normal group, microinfarction patients were older, had more congestive heart failure, required more intensive monitoring and therapy during longer stays, and sustained a higher in-hospital mortality rate. Thus, these microinfarction patients are at increased risk and therefore warrant aggressive treatment and further evaluation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-8703
pubmed:author
pubmed:issnType
Print
pubmed:volume
111
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1041-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Elevated CK-MB with normal total creatine kinase in suspected myocardial infarction: associated clinical findings and early prognosis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.