Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-6-27
pubmed:abstractText
The regional absence of perfusion in the territory situated downstream of a lung embolus can be visualized using a gamma camera and 99m Technetium labelled macroaggregated albumin of albumin microspheres. This is a simple and atraumatic procedure. Following intravenous injection these particles are blocked in the pulmonary capillaries, their distribution in the lungs being proportional to the regional perfusion. A normal perfusion scan virtually excludes pulmonary embolism. Pulmonary embolism typically causes a wedge shaped perfusion defect at one or more sites. However, a regional perfusion defect by itself can not be regarded as a specific sign of pulmonary embolism, since it may be found in many other lung diseases. In most pulmonary diseases matched perfusion and ventilation defects are found. In the case of pulmonary embolism ventilation is usually normal in the ischemic area. To differentiate pulmonary embolism from other lung diseases, a ventilation scan is therefore mandatory in addition to the perfusion scan. For this purpose radioactive inert gases such as 81mKrypton or 133Xenon may be used, or aerosols labelled with 99mTechnetium. Each of these methods has its own advantages and shortcomings. Criteria which may be helpful for the interpretation of combined ventilation/perfusion scans are presented.
pubmed:language
dut
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5458
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
85-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Isotope studies in the detection of pulmonary embolism].
pubmed:publicationType
Journal Article, English Abstract