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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-7-17
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pubmed:abstractText |
Twenty-five patients with locally advanced but resectable adenocarcinoma of the stomach were given concomitant postoperative radiotherapy to the tumor bed and chemotherapy with 5-Fluorouracil (5-FU). Twenty-two of the patients had regional lymph node involvement and seven had residual tumor in the surgical margins. Radiotherapy was delivered to a total dose of 5,000 rads in 7 weeks with a two-week split. 5-FU was given daily the first 3 days of each treatment period and was then continued weekly for a minimum of 1 year. At a median follow-up time of 19 months, 11 patients have relapsed, two locally and nine distally, and all have died. Thirteen patients remain alive, all but one disease-free, for a median of 21 months from diagnosis. One additional patient died of unrelated causes, free of tumor. The actuarial median survival for the whole group stands at 33 months with a projected 5-year survival of 40%. Treatment has been well tolerated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-4790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3713191-Adenocarcinoma,
pubmed-meshheading:3713191-Adult,
pubmed-meshheading:3713191-Aged,
pubmed-meshheading:3713191-Combined Modality Therapy,
pubmed-meshheading:3713191-Female,
pubmed-meshheading:3713191-Fluorouracil,
pubmed-meshheading:3713191-Humans,
pubmed-meshheading:3713191-Male,
pubmed-meshheading:3713191-Middle Aged,
pubmed-meshheading:3713191-Radiotherapy,
pubmed-meshheading:3713191-Semustine,
pubmed-meshheading:3713191-Stomach Neoplasms
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pubmed:year |
1986
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pubmed:articleTitle |
Combined 5-fluorouracil (5-FU) and radiation therapy following resection of locally advanced gastric carcinoma.
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pubmed:publicationType |
Journal Article
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