Linked Life Data

3711983

Source:http://linkedlifedata.com/resource/pubmed/id/3711983

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-7-1
pubmed:abstractText
Embryos of Xenopus laevis and Ambystoma mexicanum were continually immobilized from premotile stages of development to stages at which normally reared embryos were swimming well. Immobilization was achieved through exposure to solutions of chloretone, lidocaine, or alpha-bungarotoxin. At a number of stages after recovery from the drugs, spontaneous and stimulated behaviors were extensively quantified. Immobilization of Ambystoma embryos resulted in temporary defects in musculoskeletal development. In contrast, treated Xenopus embryos could not be distinguished from controls by simple visual observation within minutes to hours after removal from the drug solutions. Quantifications of behavior revealed, however, a transient period of 24-48 hr during which treated embryos exhibited consistently reduced measures of stimulated swimming, while showing an increase in frequency of spontaneous movements. Detailed behavioral testing could detect no permanent effects of chronic immobilization in either species after this initial period of recovery. The results are discussed in reference to the classic works of Harrison (1904), Carmichael (1926, 1927), and Matthews and Detwiler (1926).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0270-6474
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1332-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Behavioral development in the absence of neural activity: effects of chronic immobilization on amphibian embryos.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.