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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1986-7-23
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pubmed:abstractText |
Regional amino acid concentrations were measured in rat brain fixed by microwave irradiation at three levels of elevated atmospheric pressure corresponding to different phases of the high-pressure neurological syndrome [20 atmospheres absolute (ATA), no clinical signs; 60 ATA, tremor; 85 ATA, severe tremor and myoclonic jerks]. No changes in amino acid content occurred at 20 or 60 ATA. At 85 ATA glutamine content increased in hippocampus, striatum, cerebellum, and substantia nigra, and gamma-aminobutyric acid content increased in hippocampus. It is suggested that enhanced glutamate release in various subcortical structures contributes to the myoclonic activity observed at 85 ATA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-3042
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3711908-Amino Acids,
pubmed-meshheading:3711908-Animals,
pubmed-meshheading:3711908-Atmospheric Pressure,
pubmed-meshheading:3711908-Behavior, Animal,
pubmed-meshheading:3711908-Brain,
pubmed-meshheading:3711908-High Pressure Neurological Syndrome,
pubmed-meshheading:3711908-Male,
pubmed-meshheading:3711908-Rats,
pubmed-meshheading:3711908-Rats, Inbred Strains,
pubmed-meshheading:3711908-Tissue Distribution
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pubmed:year |
1986
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pubmed:articleTitle |
Regional amino acid concentration in the brains of rats exposed to high pressures.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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