Linked Life Data

3707753

Source:http://linkedlifedata.com/resource/pubmed/id/3707753

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-6-27
pubmed:abstractText
The molecular weight of sodium hyaluronate in human amniotic fluid was determined by gel chromatography. Pooled samples from 16 weeks of gestation exhibited a broad molecular weight distribution (Mw = 3 X 10(5); Mn = 6 X 10(4)). Samples taken at 40 weeks showed a low molecular weight fraction (M less than 10(5) presumably of fetal origin, and a high molecular weight fraction (M greater than 10(6) which varied considerably, indicating a nonfetal origin. No hyaluronate degrading activity was detected in the fluid. In a case of renal dysplasia, only minute amounts of hyaluronate were found. These findings are in accordance with a renal excretion of a low molecular weight hyaluronate from the fetus. In 12 cases with proven neural tube defects, there was no significant difference in hyaluronate level and molecular weight compared to normal controls.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0885-4505
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-26
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
The molecular weight of sodium hyaluronate in amniotic fluid.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't