Linked Life Data

3707562

Source:http://linkedlifedata.com/resource/pubmed/id/3707562

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1986-6-3
pubmed:abstractText
Two groups of each 6 male hooded rats with bilateral symmetrical lesions in the anterior dorsolateral tegmentum including parts of the anterior and posterior pretectal nuclei and two sham-operated control groups were compared in different avoidance paradigms. The acquisition of conditioned avoidance responses (CAR) in a Y-maze was significantly retarded in lesioned rats and remained definitely on a lower performance level. Their reaction times (RTs) were significantly prolonged. Brightness discrimination was severely impaired. They had evidently troubles to correct their erroneous runs. After preoperative training lesioned rats had no retention deficit in the Y-maze performance, neither different RTs nor changes of running speed, but a deficit in brightness discrimination. Postoperative acquisition of CAR in a jump test was impossible. Retention of preoperatively learnt CAR in the jump test was zero, relearning was impossible reaching not more than 40% CAR performance after 8 sessions. The behavioural syndrome was different from other tegmental lesion types. Impaired brightness discrimination and vertical visual orientation are main symptoms of the more complex disturbance of goal-directed behaviour.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0232-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
477-83
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
The pretectal region of the rat participates in the regulation of goal-directed behaviour.
pubmed:publicationType
Journal Article