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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-3
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pubmed:dateCreated |
1986-6-6
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pubmed:abstractText |
Cysticerci parasitize several mammalian species, including man, in which the parasitic disease shows unique characteristics since cysticerci are established mainly in immunologically privileged sites and can survive for many years. The study of the human immune response to cysticerci is helpful in diagnosis and could perhaps also aid in preventing or curing the disease. Anti-cysticercus IgG can be detected in serum and cerebrospinal fluid (CSF) of almost all patients with neurocysticercosis, by the enzyme-linked immunosorbent assay (ELISA); antibodies of the other classes are found less frequently. Antibodies react with up to eight Taenia solium cysticercus antigens, mainly with antigen B. This antigen has an affinity for collagen and is not commonly found in the CSF. It could therefore be participating in vasculitic processes spotted in the brain of neurocysticercotic patients. Immunoglobulins are also identified on the surface of the parasites: IgG is detected on parasites obtained from various tissues; IgM, IgA and IgE mostly on extracerebral cysticerci. We discuss the possibility of extraneural cysticerci being destroyed by the immune response of the host whereas natural aging may cause brain cysticerci death.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Antigen-Antibody Complex,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Helminth,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin A,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin M
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0304-4017
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-102
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3705428-Antibodies,
pubmed-meshheading:3705428-Antigen-Antibody Complex,
pubmed-meshheading:3705428-Antigens, Helminth,
pubmed-meshheading:3705428-Central Nervous System Diseases,
pubmed-meshheading:3705428-Cysticercosis,
pubmed-meshheading:3705428-Cysticercus,
pubmed-meshheading:3705428-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:3705428-Host-Parasite Interactions,
pubmed-meshheading:3705428-Humans,
pubmed-meshheading:3705428-Immunoglobulin A,
pubmed-meshheading:3705428-Immunoglobulin E,
pubmed-meshheading:3705428-Immunoglobulin G,
pubmed-meshheading:3705428-Immunoglobulin M,
pubmed-meshheading:3705428-Lymphocyte Activation,
pubmed-meshheading:3705428-Taenia
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pubmed:year |
1986
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pubmed:articleTitle |
Host--parasite relationship in cysticercosis: immunologic study in different compartments of the host.
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pubmed:publicationType |
Journal Article
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