Linked Life Data

3704779

Source:http://linkedlifedata.com/resource/pubmed/id/3704779

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-6-13
pubmed:abstractText
With increasing use of chemonucleolysis, interest and use of discography is at an all-time high. Various reports in past years have disagreed on the safety and efficacy of intradiscal injections of contrast mediums. This experimental study was devised to determine the effects of discography on the gross and histologic appearance of the lumbar intervertebral disc. Through a laparotomy approach, five lumbar discs in ten dogs were exposed. In each dog, one disc served as a control, another punctured with a needle, and the others injected with metrizamide, hypaque, or saline, At 2, 4, 6, 8, and 10 weeks postoperative, two dogs were killed at each time interval. Examination of the discs revealed no gross differences between any of the groups. The normal gross architecture of the concentric annulus and gelatinous nucleus was maintained in all specimens. This study found no evidence that discography results in gross or histologic damage to the intervertebral disc. It does not appear that discography will predispose a normal intervertebral disc to herniate. Discography alone appears to be a safe diagnostic procedure with no experimental evidence of any untoward gross or histologic effects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0362-2436
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
26-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:articleTitle
The effect of discography on the canine intervertebral disc.
pubmed:publicationType
Journal Article