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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-5-27
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pubmed:abstractText |
The authors report three cases of bronchiolitis obliterans occurring during treatment of rheumatoid arthritis with D-penicillamine after 4, 6 and 8 months of treatment and when the rheumatoid arthritis was in a state of remission. None of these patients (2 sero-positive and 1 sero-negative) present any past history of pulmonary or bronchial disease. The daily dosage of D-penicillamine never exceeded 600 mg. High dose corticosteroid therapy was unable to improve the clinical signs or the respiratory function tests, which were severely disturbed. After 15 months to 3 years, the respiratory signs deteriorated in 2 of the 3 patients. The onset of dyspnea and cough, in the absence of a seasonal infection, in a subject treated with D-penicillamine should raise the possibility of this very serious complication.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0035-2659
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3704508-Adult,
pubmed-meshheading:3704508-Arthritis, Rheumatoid,
pubmed-meshheading:3704508-Bronchitis,
pubmed-meshheading:3704508-Female,
pubmed-meshheading:3704508-Humans,
pubmed-meshheading:3704508-Middle Aged,
pubmed-meshheading:3704508-Penicillamine,
pubmed-meshheading:3704508-Pulmonary Fibrosis
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pubmed:year |
1986
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pubmed:articleTitle |
[3 cases of obliterating bronchiolitis during treatment of rheumatoid polyarthritis with D-penicillamine].
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|