Linked Life Data

3703905

Source:http://linkedlifedata.com/resource/pubmed/id/3703905

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-6-17
pubmed:abstractText
Cholinergic activity of the caudate-putamen (CPU) is crucial for the acquisition of aversively-reinforced behaviors (active and passive avoidance). To determine whether this activity is also involved in the acquisition of a positively-rewarded behavior, in the present experimental series the effects of scopolamine applications to the antero-dorsal or postero-dorsal aspects of the striatum on auto-shaping were assessed. The auto-shaping procedure that was used allowed rats to learn to bar press at their own rate. It was found that scopolamine injection into either region of the CPU produced a marked retardation in the acquisition of the conditioned behavior. These results indicate that cholinergic activity of the striatum is critically involved in the early phases of positively-reinforced learning.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
715-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Is cholinergic activity of the striatum involved in the acquisition of positively-motivated behaviors?
pubmed:publicationType
Journal Article