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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-6-13
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pubmed:abstractText |
Amyloid deposits in the temporal artery were observed 40 years ago, but the presence of vascular ischemic symptoms in patients with amyloidosis has been infrequently recognized. We examined 22 patients who had typical jaw claudication with biopsy-proven primary amyloidosis. In none was vasculitis a contributing cause of the claudication. However, two patients were misdiagnosed initially as having temporal arteritis and polymyalgia rheumatica and were treated with corticosteroids, which resulted in significant toxicity. Subsequent temporal artery biopsy revealed extensive amyloid deposits in both patients. Jaw claudication was associated with other ischemic vascular symptoms, such as arm or calf claudication. The median survival for the subset of patients with amyloidosis and jaw claudication was 42 months, and that for the entire group of patients with amyloidosis was 12 months. Appropriate staining of temporal artery biopsy specimens is necessary for the correct diagnosis in such cases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0025-7974
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3702668-Aged,
pubmed-meshheading:3702668-Amyloidosis,
pubmed-meshheading:3702668-Carpal Tunnel Syndrome,
pubmed-meshheading:3702668-Diagnosis, Differential,
pubmed-meshheading:3702668-Humans,
pubmed-meshheading:3702668-Intermittent Claudication,
pubmed-meshheading:3702668-Jaw Diseases,
pubmed-meshheading:3702668-Male,
pubmed-meshheading:3702668-Middle Aged,
pubmed-meshheading:3702668-Multiple Myeloma,
pubmed-meshheading:3702668-Polymyalgia Rheumatica,
pubmed-meshheading:3702668-Temporal Arteries
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pubmed:year |
1986
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pubmed:articleTitle |
Jaw claudication in primary systemic amyloidosis.
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pubmed:publicationType |
Journal Article,
Case Reports
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