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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1986-6-9
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pubmed:abstractText |
The sensitivity of the radiofibrinogen test was investigated to determine the accuracy of the test in diagnosis of venographically proven venous thrombosis in 70 heparinized patients. 125J-fibrinogen was administered between 2 h and 4 days (mean: 1.5 days) after initiating heparin therapy. There were two criteria for a positive test: if the difference between the counts for adjacent points on the same leg or equivalent sites on opposite legs was at least 15%; and/or if there were three adjacent points each with counts greater than 5% that of the same three points on the other leg. The fibrinogen uptake test was positive at the first examination in 67 of 70 patients, giving a sensitivity of 96%. The respective frequencies of truly abnormal results for the 3 X 5% and the 1 X 15% criteria were 94% and 71%. As far as localization and extension of thrombosis were concerned, the fibrinogen uptake test agreed with phlebography in 73% of the cases, when the counts in the groin and the upper third of the thigh were ignored. The 125J-fibrinogen uptake test is an accurate method for detecting established deep leg vein thrombosis even in anticoagulated patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0023-2173
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-30
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3702281-Adult,
pubmed-meshheading:3702281-Aged,
pubmed-meshheading:3702281-Female,
pubmed-meshheading:3702281-Fibrinogen,
pubmed-meshheading:3702281-Heparin,
pubmed-meshheading:3702281-Humans,
pubmed-meshheading:3702281-Infusions, Parenteral,
pubmed-meshheading:3702281-Iodine Radioisotopes,
pubmed-meshheading:3702281-Male,
pubmed-meshheading:3702281-Middle Aged,
pubmed-meshheading:3702281-Phlebography,
pubmed-meshheading:3702281-Thrombophlebitis
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pubmed:year |
1986
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pubmed:articleTitle |
Sensitivity of 125J-fibrinogen uptake test for diagnosis of established venous thrombosis in heparinized patients.
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pubmed:publicationType |
Journal Article
|