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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1986-6-12
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pubmed:abstractText |
Eighty-five samples of chorionic villi from women undergoing prenatal diagnosis at 8 to 12 weeks' gestation were subjected to cytogenetic analysis. Samples were prepared by a direct technique that permits limited analysis within two hours and by a short-term culture technique that permits detailed structural analysis within one week. An adequate number of cell divisions for cytogenetic analysis was obtained from 96% of living fetuses. Using both the direct technique and short-term culture, satisfactory banded chromosomal preparations were made in 93% of cases. Eleven of 12 pregnancies (92%) shown by ultrasound to be dead shortly before sampling, had cytogenetic abnormalities. Further studies are needed to develop banding definition equivalent to that available on cultured amniocytes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0340-6717
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3699820-Adult,
pubmed-meshheading:3699820-Chorionic Villi,
pubmed-meshheading:3699820-Chromosome Aberrations,
pubmed-meshheading:3699820-Chromosome Deletion,
pubmed-meshheading:3699820-Female,
pubmed-meshheading:3699820-Humans,
pubmed-meshheading:3699820-Karyotyping,
pubmed-meshheading:3699820-Maternal Age,
pubmed-meshheading:3699820-Ploidies,
pubmed-meshheading:3699820-Pregnancy,
pubmed-meshheading:3699820-Pregnancy, High-Risk,
pubmed-meshheading:3699820-Prenatal Diagnosis
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pubmed:year |
1986
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pubmed:articleTitle |
Cytogenetic analysis of chorionic villi: a technical assessment.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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