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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-6-18
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pubmed:abstractText |
Patients attending a general hospital for various reasons were screened for raised serum gamma glutamyltransferase (gamma-GT) and positive blood alcohol concentration (BAC). The results served as objective biochemical tests of heavy drinking. Among 419 individuals, 50 (11.9%) met these requirements and blood samples were used to determine the presence of low molecular mass aliphatic diols. 1,2-Propanediol, 2,3-butanediol and 2,2-dimethyl-1,3-propanediol were determined by gas liquid chromatography-mass spectrometry (GC-MS). In patients with blood ethanol concentration less than 2 mmol/l, 1,2-propanediol and 2,2-dimethyl-1, 3-propanediol mainly occurred together at median concentrations of about 200 mumol/l. When blood ethanol was 2-42 mmol/1,2,3-butanediol was also present covering a wide concentration range: three patients had concentrations between 6 and 10 mmol/l. There was no apparent correlation between the concentration of 2,3-butanediol and the concentration of blood ethanol. The diols were below the limits of detection in blood from nonintoxicated control individuals and hospital in-patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3-butylene glycol,
http://linkedlifedata.com/resource/pubmed/chemical/Butylene Glycols,
http://linkedlifedata.com/resource/pubmed/chemical/Ethanol,
http://linkedlifedata.com/resource/pubmed/chemical/Propylene Glycol,
http://linkedlifedata.com/resource/pubmed/chemical/Propylene Glycols
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0009-8981
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
117-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3698310-Adolescent,
pubmed-meshheading:3698310-Adult,
pubmed-meshheading:3698310-Aged,
pubmed-meshheading:3698310-Butylene Glycols,
pubmed-meshheading:3698310-Ethanol,
pubmed-meshheading:3698310-Female,
pubmed-meshheading:3698310-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:3698310-Humans,
pubmed-meshheading:3698310-Male,
pubmed-meshheading:3698310-Middle Aged,
pubmed-meshheading:3698310-Propylene Glycol,
pubmed-meshheading:3698310-Propylene Glycols
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pubmed:year |
1986
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pubmed:articleTitle |
Occurrence of short chain aliphatic diols in human blood: identification by gas chromatography-mass spectrometry.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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