Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-2-20
pubmed:abstractText
Classically, the stability of the lacrimal film is due to the surfacing of the epithelial surface by the mucus produced by the goblet cells. However, there are many objections to this hypothesis. Deducing from electron microscopy of the epithelial cells, which shows vesicles in the superficial layer and glycocalix threads on the microvilli and other clinical facts, we think that the surfacing agent is not mucus but glycocalix. The disappearance of goblet cells during sicca syndrome is not the cause but the result of the dryness. Epithelial cell integrity is essential for the stability of the tear film and therapeutics must aim at regenerating these cells rather than only replacing the lacrimal film by tear substitute.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0030-3755
pubmed:author
pubmed:issnType
Print
pubmed:volume
195
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
119-24
pubmed:dateRevised
2007-9-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
A new hypothesis on tear film stability.
pubmed:affiliation
Hôpital des Quinze-Vingts, Paris, France.
pubmed:publicationType
Journal Article