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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1988-2-17
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pubmed:abstractText |
Cysteine sulfinate (CSA) was shown to increase 45Ca2+ permeability of plasma membrane of synaptosomes isolated from rat brain. The 45Ca2+ enter through a system which has properties different from those of voltage dependent Ca2+ channels or Na+/Ca2+ exchange. The effect of CSA appeared to be mediated by highly specific receptors saturable by ligand. The high concentrations of CSA required (mM) suggest this amino acid is not the physiological agonist for the receptors.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0304-3940
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3696486-Amino Acids,
pubmed-meshheading:3696486-Animals,
pubmed-meshheading:3696486-Brain,
pubmed-meshheading:3696486-Calcium,
pubmed-meshheading:3696486-Calcium Channel Blockers,
pubmed-meshheading:3696486-Cell Membrane Permeability,
pubmed-meshheading:3696486-Cysteine,
pubmed-meshheading:3696486-Male,
pubmed-meshheading:3696486-Neurotransmitter Agents,
pubmed-meshheading:3696486-Rats,
pubmed-meshheading:3696486-Rats, Inbred Strains,
pubmed-meshheading:3696486-Synaptosomes
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pubmed:year |
1987
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pubmed:articleTitle |
Cysteine sulfinate modulated calcium permeability in synaptosomes from rat brain.
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pubmed:affiliation |
Department of Biochemistry and Biophysics, Medical School, University of Pennsylvania, Philadelphia 19104-6059.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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